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  • Pubblicazione
    L'Ex Europa orientale. I paesi dell'est europeo alle prese con la modernità
    (Passerino, 2025) ;
    Randazzo, Francesco
    Dopo la caduta dei regimi comunisti dell’Europa centro-orientale, chi si aspettava un’Europa più “democratica” potrebbe essere stato ampiamente deluso e non perché dalle ceneri dei governi comunisti non siano “sorti” governi democratici ma perché quest’ultimo termine, adattato alle esperienze storiche e alla tradizione di quest’area, ha creato modelli ibridi vagamente ispirati a quelli culturali occidentali e si è colorato, con buona frequenza, di caratteristiche sui generis ampiamente appoggiate dalla popolazione. Il passato, neanche tanto remoto di quest’area, ha inciso sulle scelte politiche e sociali operate dai partiti andati al potere dopo il crollo del muro di Berlino. Sarebbe davvero arduo tratteggiare in una sintesi, la quantità di riflessioni che uno storico può fare conoscendo le diverse storie nazionali ma proveremo a farlo, non tralasciando quelle che sono le peculiarità storiche e i percorsi di formazione delle identità statuali all’interno di un sistema complesso di popoli ed etnie per secoli in balia di tre imperi multietnici, quello turco-ottomano, quello austro-ungarico e infine quello russo. Questa regione europea continua a trasmettere suggestioni generalmente incomprese sulla post-modernità che spesso sembrano richiamare antiche e nostalgiche pretese di grandeur che hanno reso alcune élite etnopolitiche particolarmente agguerrite durante l’età federale e durante la guerra civile degli anni Novanta dello scorso secolo. Mezzo secolo di socialismo reale, indagato e declinato in ogni suo aspetto dallo storico Antonello Folco Biagini, spazzato via in poco meno di due anni, dal 1989 al 1991, un arco di tempo che ha ricollocato lo spazio est e centroeuropeo all’interno della secolare storia europea seppur confinandolo in una sorta di mondo parallelo.
  • Pubblicazione
    Search for light pseudoscalar boson pairs produced from Higgs boson decays using the 4 tau and 2 mu 2 tau final states in proton-proton collisions at sqrt(s) = 13 TeV
    ( 2026)
    BABBAR, J.
    ;
    BELFORTE, S.
    ;
    ;
    CASARSA, M.
    ;
    COSSUTTI, F.
    ;
    DE LEO, K.
    ;
    ;
    ET AL (the CMS Collaboration)
    A search for a pair of light pseudoscalar bosons (a1) produced in the decay of the 125 GeV Higgs boson is presented. The analysis examines decay modes where one a1 decays into a pair of tau leptons and the other decays into either another pair of tau leptons or a pair of muons. The a1 boson mass probed in this study ranges from 4 to 15 GeV. The data sample was recorded by the CMS experiment in proton-proton collisions at a center-of-mass energy of 13 TeV and corresponds to an integrated luminosity of 138 fb−1. No excess above standard model (SM) expectations is observed. The study combines the 4τ and 2μ2τ channels to set upper limits at 95% confidence level (CL) on the product of the Higgs boson production cross section and the branching fraction to the 4τ final state, relative to the Higgs boson production cross section predicted by the SM. In this interpretation, the a1 boson is assumed to have Yukawa-like couplings to fermions, with coupling strengths proportional to the respective fermion masses. The observed (expected) upper limits range between 0.007 (0.011) and 0.079 (0.066) across the mass range considered. The results are also interpreted in the context of models with two Higgs doublets and an additional complex singlet field (2HD+S). The tightest constraints are obtained for the Type III 2HD+S model. In this case, assuming the Higgs boson production cross section equals the SM prediction, values of the branching ratio for the Higgs boson decay into a pair of a1 bosons exceeding 16% are excluded at 95% CL for a1 boson masses between 5 and 15 GeV and tan β > 2, with the exception of scenarios in which the a1 boson mixes with charm or bottom quark-antiquark bound states.
  • Pubblicazione
    Blood biomarkers of response to concomitant intratympanic and systemic corticosteroids treatment for idiopathic sudden sensorineural hearing loss
    ( 2026) ;
    Costariol, Ludovica
    ;
    Cavallo-Ronchi, Federico
    ;
    Sia, Egidio
    ;
    Zucchini, Simone
    ;
    Purpose: To evaluate the prognostic value of hematological inflammatory biomarkers in predicting hearing recovery in patients with idiopathic sudden sensorineural hearing loss (ISSNHL) treated with combined systemic and intratympanic corticosteroids. Methods: This retrospective study included 125 patients diagnosed with ISSNHL between 2012 and 2021 who received both oral prednisone and intratympanic methylprednisolone. Clinical data and pre-treatment blood samples were collected. Inflammatory indices including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI) were calculated. Hearing outcomes were classified as complete, partial, or no recovery based on pure tone average (PTA) thresholds. Univariate and multivariable logistic regression analyses were performed to identify predictors of recovery. Results: Of the 125 patients, 33 (26.4%) had no recovery, 50 (40.0%) partial recovery, and 42 (33.6%) complete recovery. Dizziness, current smoking, delayed treatment initiation (> 7 days), elevated triglycerides (≥ 98 mg/dL), and high PLR (≥ 142) were independently associated with a lower probability of hearing recovery. A higher LMR (≥ 3.0) showed a positive trend but did not reach statistical significance in adjusted models. Conclusions: In patients with ISSNHL treated with dual-route corticosteroids, several clinical and hematologic factors, particularly elevated PLR and delayed treatment, are independently associated with reduced odds of hearing recovery. Inflammatory blood markers may serve as accessible prognostic tools to support early risk stratification.
  • Pubblicazione
    Baldo furioso? Per il commento a Baldus P XII, 169-365
    ( 2025)
    Federico Baricci
    The article reflects on some of the problems posed by the commentary to Folengo’s Baldus, focusing in particular on the episode of “raging Orlando” in the first edition of the work: Paganini (1517), XII, 169-365. The introduction briefly presents the different versions of the macaronic masterpiece and provides a quick overview of studies regarding the editions and commentaries dedicated to them. The first paragraph addresses a question of precise interpretation, clarifying througha wide range of references the meaning of the phrase ad ramazonem and the lexeme ramazonus, and hypothesizing that these are lexical elements that macaronics draws primarily from a tradition of ‘minor’ chivalric literature. The second paragraph addresses an intertextual issue concerning the entire construction of the episode, for which it is suggested, albeit tentatively, that Folengo had in mind the episode of Orlando’s madness in the first edition (A, 1516) of Ariosto’s Furioso.
  • Pubblicazione
    White-Sutton Syndrome: Insight of an Italian Cohort of 19 Subjects
    ( 2026)
    Anna Facchini
    ;
    Maria Pina Concas
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    Stefania Zampieri
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    Iris Scala
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    Claudio Graziano
    ;
    Anna Maria Innoceta
    ;
    Marina Trivisano
    ;
    Angela De Dominicis
    ;
    Gabriele Trimarchi
    ;
    Livia Garavelli
    ;
    Margherita Baldassarri
    ;
    Ilaria De Maggio
    ;
    Francesca Mari
    ;
    Donatella Greco
    ;
    White-Sutton syndrome (WHSUS) is a rare neurodevelopmental disorder due to pathogenic variants in the POGZ gene. Its phenotype includes developmental delay, behavioral dysfunctions, hypotonia, and dysmorphic features. The condition is still poorly known: comprehensive clinical descriptions and exhaustive genotype-phenotype correlations are lacking, limiting diagnostic and therapeutic advancements. Here, we report molecular, clinical, and instrumental data from the first and largest Italian cohort (19 patients). Our results highlight the importance of an extensive approach at the time of diagnosis-including early nutritional support for preventing obesity-related complications and instrumental screening for congenital malformations. Preliminary data suggest that splicing variants could be associated with more severe phenotypes. This study provides valuable new insights into WHSUS and represents a significant step towards its comprehension.