Electro-osmotic flows are a means of circulating polar fluids through microchannels without resorting to mechanical pumping. The lack of moving parts, of noise and the ease of integration in silicon chips make them an interesting option for microchip cooling and miniaturized total analysis systems. This paper describes an optimization in terms of first- and second-law analysis of the cross-section of a microchannel subject to electro-osmotic flow. Starting from rectangular cross-sections of different aspect ratios, its corners are progressively smoothed and the resulting Poiseuille and Nusselt numbers computed. Performance evaluation criteria are then used to assess the change in, among others, heat transfer rate, temperature difference between wall and bulk fluid, and equivalent pumping power. The entropy number is also computed and the results commented. It is found that the latter criterion highlights a configuration of minimum entropy generation, whereas the trends of the heat transfer and temperature difference are opposite to that of the equivalent pumping power.
