GARDOSSI, Lucia

ORCID iD: https://orcid.org/0000-0002-8908-2625 107 manuscripts on indexed journals, 6 book chapters, 5 patents Scopus – Total citations: 3423; From 2012: 2612 H index 25 EDUCATION 1982-1988: Univ.Trieste. Master in Medicinal Chemistry and Technology, (with honor). 1991-1993: Univ. Trieste. PhD in Medicinal Chemistry. 1989-1991: Massachusetts Institute of Technology, Department of Chemistry. Cambridge, USA. Researcher associate PROFESSIONAL EXPERIENCE 2017: habilitation as full professor in: Organic Chemistry; Chemistry and Biotechnology of fermentation; Chemical Basis of Technologies 2005-on: Associate prof. organic chemistry. 1995-2005: Assistant prof. organic chemistry. 1993-1995: POLY-TECH Soc. Co., Senior researcher. 2007: co-founder of SPRIN S.r.l. -Technologies for sustainable chemistry. 2009: ICS-UNIDO consultant. 2004-2005 Consultant of DSM (Geleen , NL ). ASSIGNMENTS -Since 2020: Member of the of the Scientific and Technical Committee of Assobioplastiche, Italy -Since 2020: member of the Executive Board of “Biomaterials” of the “European Federation of Biotecnology”. -2020: member of the working group of Italian " Ministero dell’Ambiente e della Tutela del Territorio e del Mare" on Bioeocnomy -2020: member of the expert group for the “ BBI JU Project Portfolio and KPIs Validation” of Horizon 2020 -Since 2019: Member of the National Bioeconomy Coordination Board of the Italian Presidency of Council of Ministers -2017-on:Coordinator of the CTS of the National Technology Cluster for Circular Bioeconomy SPRING; - 2017-on: member of the board of the National Technology Cluster “SPRING”. -Since 2005: Italian representative inside the scientific board of ESAB (the European Session of Applied Biocatalysis of EFB) -2017: Rapporteur European Commission Mid-term evaluation of Horizon 2020 programme “Bio Based Industry Joint Undertaking”. -2020: Member of the expert group for the writing of Italian PNR (National Research Plan). Ministero Istruzione Università e Ricerca-MIUR, Italy - 2013 -2016: European Commission: vice chair of the Advisory Group for H2020 (SC2) Main international research projects (scientific responsible) -2021-23: Marie Curie grant agreement 101029444, “Sustainable route for circularity of renewable polyesters”. -2019: H2020, INTERFACE project: Heterogenous biocatalytic reaction cascades training network. Project ID: 860414. -2019-2022: “PRIME project”: Process and products for green chemistry”, (EU-PORFESR) -Scientific coordinator FP7 Project “IRENE” (In silico Rational Engineering of Novel Enzymes.) Budget : 4Milions €. -2001-2004: EU FP5- "COMBIOCAT" Project (Grant agreement QLK3-2000-00160). "Evolutionary discovery of novel drugs by orchestration of polymer-supported combinatorial bio-/chemistry." -2012-2013: FP7 REFINE (REnewable FunctIoNal matErial – Training material scientists for a sustainable polymer industry) scientific responsible for the spin-off SPRIN technology for sustainable chemistry. - 2002 -2022: Scientific responsible for 15 industrially funded projects for about 5 M €. Main Italian research projects -PRIN 2017: “CARDIGAN” project: cardoon valorisation by integrated biorefineries”, -PRIN 2002: Applicazione di cellule intere liofilizzate in solventi organici monofasici. HONOURS AND AWARDS -2020: XVI edition of the "Tecnovisionarie 2020" Award, promoted by the Women and Technology association. "Interpreting the circular economy through innovation," Special Research and Science Award -2006: Best business plan for "Start Cup 2006" competition, Università degli Studi di Trieste. Editorial experience -Since 2021: Senior editor di EFB Bioeconomy Journal (Elsevier) -Since 2019: Associate editor di Frontiers Bioengineering and Biotechnology SELECTED INTERNATIONAL CONFERENCES AS INVITED SPEAKER: 2021: “From strategy to implementation: monitoring systems and indicators”, G20 Workshop on Bioeconomy in the OECD countries, Rome, Presidency of Council of Ministers, July 16, 2021. 2021: Biocatalysis for new functional bio-based polyesters, May 12 (on-line conference). 2021: Enzymatic synthesis and degradation of bio-based polyesters: non-conventional biocatalysis at the service of circularity. 6th International Conference on Biocatalysis in Non-Conventional Media – BNCM 2021 May 7th, 2021. 2019: “Evolving biocatalysis to meet Bioeconomy challenges and opportunities”. FEB Advanced course in enzymology and biocatalysis. Roma 27-31 May 2019: Biocatalysis for the targeted functionalization of bio-based polyesters and lignocellulosic materials: taking inspiration from nature. Kluyver Colloquium, Delft University of Technology – TUD, 8 March 2016: "Mastering biocatalysis complexity: from sectoral to systemic biocatalysis". Gordon Conference on Biocatalysis, Biddeford, ME, USA. 10-15 July 2016: "Integrated biocatalysis for biobased chemistry and fully renewable polyesters". BIOCAT "8th International Congress on Biocatalysis", Hamburg, August30- September 1 . 2015: "Biocatalysis for the integrated biorefineries: New perspectives for the sustainable production of biobased polyesters and biofuels" CEI-JRC European Workshop on Advanced Biofuels, Biorefinery and Bioeconomy . Bratislava, 25-27 March. 2015: “Biocatalysis for the integrated biorefineries: new perspectives for the sustainable production of bio-based polyesters and biofuels” IEA- Intertasks Workshop on biorefineries. Sassari, 5 May 2015: "Towards feasible and scalable solvent-free enzymatic synthesis of polyesters: integrating robust biocatalysts with thin film reactions." Acib conference on industrial Enzymes, Pavia 22-23, September 2014: “Novel 3D-structure based bio-informatic tools for rational engineering of promiscuous biocatalysts “ 3rd Multistep Enzyme Catalyzed Processes Congress (MECP14). Madrid, 7-10 April. 2013: Understanding feasibility and scalability of enzymatic synthesis of polyesters. PLASTiCE conference on Bioplastic Opportunities in Central Europe Slovenj Gradec, 23-24 September. 2013: “Enzymatic Catalysis For Polycondensation: Potential Impact And Technological Barriers” Austrian-Slovenian Polyer Meeting - Aspm Conference, Bled (Si) 3-5 April. 2011: “Biocatalysis in peptide synthesis: from non aqueous media to solid phase synthesis”, IBOS Open Conference on Integrating methodologies towards new synthesis approaches, Lunteren, The Netherlands 15-17 May 2010: “ Computational tools as an aid for the full exploitation of lipases’ catalytic potential”. Novel Enzymes 2010 Exeter (UK), 14-17 April 2010: Adapting biocatalysts for biorefinery processes”.Minisymposium: Enzymes and biofuels: do they fit? Workshop organised by the Dutch Biotechnological Society (NBV). Congress Centre "Regardz Eenhoorn", Amersfoort (NL). 24 November 2010: “Industrial and Environmental Biotechnology sector in Italy: State of the art and perspectives.” International Symposium on Frontiers of Industrial and Environmental Biotechnology organized by the Industrial Biotechnology (Sangyo Bio in Japanese) Group at Osaka University. Osaka 9 Febrary. 2009: “Biotechnologies in the production of biofuels and biobased chemicals” workshop on “Next generation bio-fuels and bio-refineries organized by ICS-UNIDO: Case studies for selected East European Countries”, Trieste 2-3 December 2009:-Rational Development of Industrial Biocatalysts by Combining Computational and Experimental, Methods. Academia Sinica, Taipei, Taiwan. 6 October -“Biocatalysis: the hard task of rational process development.” School of Pharmacy, National Taiwan University, Taipei, Taiwan. 6 October -“Tools for improving lipases efficiency in applied biocatalysis”, Chung-Hsin University, Taichung, Taiwan. 9 ottobre 2009. -“Combining experimental and computational methods for the rational development of biocatalyzed processes”, Chang-Geng University, Taiwan. 7 October 2009: “Rational Development of Industrial Biocatalysts by Combining Computational and Experimental Methods” Conference: “Biotech.org”, Forte dei Marmi, 20-23 May 2008: “Molecular modelling for rational design of industrial enzymes”, V International Symposium EU-Russia: Cooperation in Biotechnology, Agriculture, Forestry, Fisheries and Food in the 7th FP”, Pushchino, Russia, 2-3 October. 2007: “Biocatalysis: the Italian contribution to industrial biotechnology”, "Joint Italian Japanese meeting on The challenge of biotechnologies”, Osaka, Giappone, 16 May. 2005: “Combining experimental and computational studies as a strategy towards a more rational biocatalysis”. BIOTRANS 2005, Delft, 3-8- July RESEARCH INTERESTS AND SKILLS Biobased chemistry, bioplastics, green chemistry, biomass valorization, biocomposite materials, biocatalysis, organic chemistry, computer-aided molecular simulation of enzymes; integration of molecular dynamics, molecular mechanics, docking, molecular descriptors based on GRID force field, for biocatalysis and rational enzyme engineering, machine learning, multiobjective optimization, chemometrics, 3D QSAR. HEAD OF SCIENTIFIC COMMITTEE OF INTERNATIONAL CONFERENCES “In silico enzyme design and screening”, Trieste, 7-9 May 2012. “Bioeconomy and Bio-based Industry for the Rural Renaissance of Regions (3BiR3)”. Trieste, 23-24 May 2019. MEMBER OF SCIENTIFIC COMMITTEE OF INTERNATIONAL CONFERENCES 2014: “Novel Enzymes”, Ghent, 14-17 October Since 2012: IFIB (Italian Forum on Industrial Biotechnology and Bioeconomy). Milan, 25-26 October, 2012; Napoli, 22-23 October 2013; Genova, 25-26 September 2014; Lodi 24-25 September 2015; Vicenza 22-23 September 2016; Roma 5-6 October 2017, Torino 4-5 October 2018. 2011: “BIOTRANS 2011”, Giardini Naxos, October 2-6 2010: “Novel enzymes”, Exeter, U.K., April 11-15. 2010: 14th International Biotechnology Symposium and Exhibition, Rimini, Italy, September 14-18. 2008: “Biocatalysis in non-conventional media”, Moscow, June 12-15.

ORCID iD: https://orcid.org/0000-0002-8908-2625 107 manuscripts on indexed journals, 6 book chapters, 5 patents Scopus – Total citations: 3423; From 2012: 2612 H index 25 EDUCATION 1982-1988: Univ.Trieste. Master in Medicinal Chemistry and Technology, (with honor). 1991-1993: Univ. Trieste. PhD in Medicinal Chemistry. 1989-1991: Massachusetts Institute of Technology, Department of Chemistry. Cambridge, USA. Researcher associate PROFESSIONAL EXPERIENCE 2017: habilitation as full professor in: Organic Chemistry; Chemistry and Biotechnology of fermentation; Chemical Basis of Technologies 2005-on: Associate prof. organic chemistry. 1995-2005: Assistant prof. organic chemistry. 1993-1995: POLY-TECH Soc. Co., Senior researcher. 2007: co-founder of SPRIN S.r.l. -Technologies for sustainable chemistry. 2009: ICS-UNIDO consultant. 2004-2005 Consultant of DSM (Geleen , NL ). ASSIGNMENTS -Since 2020: Member of the of the Scientific and Technical Committee of Assobioplastiche, Italy -Since 2020: member of the Executive Board of “Biomaterials” of the “European Federation of Biotecnology”. -2020: member of the working group of Italian " Ministero dell’Ambiente e della Tutela del Territorio e del Mare" on Bioeocnomy -2020: member of the expert group for the “ BBI JU Project Portfolio and KPIs Validation” of Horizon 2020 -Since 2019: Member of the National Bioeconomy Coordination Board of the Italian Presidency of Council of Ministers -2017-on:Coordinator of the CTS of the National Technology Cluster for Circular Bioeconomy SPRING; - 2017-on: member of the board of the National Technology Cluster “SPRING”. -Since 2005: Italian representative inside the scientific board of ESAB (the European Session of Applied Biocatalysis of EFB) -2017: Rapporteur European Commission Mid-term evaluation of Horizon 2020 programme “Bio Based Industry Joint Undertaking”. -2020: Member of the expert group for the writing of Italian PNR (National Research Plan). Ministero Istruzione Università e Ricerca-MIUR, Italy - 2013 -2016: European Commission: vice chair of the Advisory Group for H2020 (SC2) Main international research projects (scientific responsible) -2021-23: Marie Curie grant agreement 101029444, “Sustainable route for circularity of renewable polyesters”. -2019: H2020, INTERFACE project: Heterogenous biocatalytic reaction cascades training network. Project ID: 860414. -2019-2022: “PRIME project”: Process and products for green chemistry”, (EU-PORFESR) -Scientific coordinator FP7 Project “IRENE” (In silico Rational Engineering of Novel Enzymes.) Budget : 4Milions €. -2001-2004: EU FP5- "COMBIOCAT" Project (Grant agreement QLK3-2000-00160). "Evolutionary discovery of novel drugs by orchestration of polymer-supported combinatorial bio-/chemistry." -2012-2013: FP7 REFINE (REnewable FunctIoNal matErial – Training material scientists for a sustainable polymer industry) scientific responsible for the spin-off SPRIN technology for sustainable chemistry. - 2002 -2022: Scientific responsible for 15 industrially funded projects for about 5 M €. Main Italian research projects -PRIN 2017: “CARDIGAN” project: cardoon valorisation by integrated biorefineries”, -PRIN 2002: Applicazione di cellule intere liofilizzate in solventi organici monofasici. HONOURS AND AWARDS -2020: XVI edition of the "Tecnovisionarie 2020" Award, promoted by the Women and Technology association. "Interpreting the circular economy through innovation," Special Research and Science Award -2006: Best business plan for "Start Cup 2006" competition, Università degli Studi di Trieste. Editorial experience -Since 2021: Senior editor di EFB Bioeconomy Journal (Elsevier) -Since 2019: Associate editor di Frontiers Bioengineering and Biotechnology SELECTED INTERNATIONAL CONFERENCES AS INVITED SPEAKER: 2021: “From strategy to implementation: monitoring systems and indicators”, G20 Workshop on Bioeconomy in the OECD countries, Rome, Presidency of Council of Ministers, July 16, 2021. 2021: Biocatalysis for new functional bio-based polyesters, May 12 (on-line conference). 2021: Enzymatic synthesis and degradation of bio-based polyesters: non-conventional biocatalysis at the service of circularity. 6th International Conference on Biocatalysis in Non-Conventional Media – BNCM 2021 May 7th, 2021. 2019: “Evolving biocatalysis to meet Bioeconomy challenges and opportunities”. FEB Advanced course in enzymology and biocatalysis. Roma 27-31 May 2019: Biocatalysis for the targeted functionalization of bio-based polyesters and lignocellulosic materials: taking inspiration from nature. Kluyver Colloquium, Delft University of Technology – TUD, 8 March 2016: "Mastering biocatalysis complexity: from sectoral to systemic biocatalysis". Gordon Conference on Biocatalysis, Biddeford, ME, USA. 10-15 July 2016: "Integrated biocatalysis for biobased chemistry and fully renewable polyesters". BIOCAT "8th International Congress on Biocatalysis", Hamburg, August30- September 1 . 2015: "Biocatalysis for the integrated biorefineries: New perspectives for the sustainable production of biobased polyesters and biofuels" CEI-JRC European Workshop on Advanced Biofuels, Biorefinery and Bioeconomy . Bratislava, 25-27 March. 2015: “Biocatalysis for the integrated biorefineries: new perspectives for the sustainable production of bio-based polyesters and biofuels” IEA- Intertasks Workshop on biorefineries. Sassari, 5 May 2015: "Towards feasible and scalable solvent-free enzymatic synthesis of polyesters: integrating robust biocatalysts with thin film reactions." Acib conference on industrial Enzymes, Pavia 22-23, September 2014: “Novel 3D-structure based bio-informatic tools for rational engineering of promiscuous biocatalysts “ 3rd Multistep Enzyme Catalyzed Processes Congress (MECP14). Madrid, 7-10 April. 2013: Understanding feasibility and scalability of enzymatic synthesis of polyesters. PLASTiCE conference on Bioplastic Opportunities in Central Europe Slovenj Gradec, 23-24 September. 2013: “Enzymatic Catalysis For Polycondensation: Potential Impact And Technological Barriers” Austrian-Slovenian Polyer Meeting - Aspm Conference, Bled (Si) 3-5 April. 2011: “Biocatalysis in peptide synthesis: from non aqueous media to solid phase synthesis”, IBOS Open Conference on Integrating methodologies towards new synthesis approaches, Lunteren, The Netherlands 15-17 May 2010: “ Computational tools as an aid for the full exploitation of lipases’ catalytic potential”. Novel Enzymes 2010 Exeter (UK), 14-17 April 2010: Adapting biocatalysts for biorefinery processes”.Minisymposium: Enzymes and biofuels: do they fit? Workshop organised by the Dutch Biotechnological Society (NBV). Congress Centre "Regardz Eenhoorn", Amersfoort (NL). 24 November 2010: “Industrial and Environmental Biotechnology sector in Italy: State of the art and perspectives.” International Symposium on Frontiers of Industrial and Environmental Biotechnology organized by the Industrial Biotechnology (Sangyo Bio in Japanese) Group at Osaka University. Osaka 9 Febrary. 2009: “Biotechnologies in the production of biofuels and biobased chemicals” workshop on “Next generation bio-fuels and bio-refineries organized by ICS-UNIDO: Case studies for selected East European Countries”, Trieste 2-3 December 2009:-Rational Development of Industrial Biocatalysts by Combining Computational and Experimental, Methods. Academia Sinica, Taipei, Taiwan. 6 October -“Biocatalysis: the hard task of rational process development.” School of Pharmacy, National Taiwan University, Taipei, Taiwan. 6 October -“Tools for improving lipases efficiency in applied biocatalysis”, Chung-Hsin University, Taichung, Taiwan. 9 ottobre 2009. -“Combining experimental and computational methods for the rational development of biocatalyzed processes”, Chang-Geng University, Taiwan. 7 October 2009: “Rational Development of Industrial Biocatalysts by Combining Computational and Experimental Methods” Conference: “Biotech.org”, Forte dei Marmi, 20-23 May 2008: “Molecular modelling for rational design of industrial enzymes”, V International Symposium EU-Russia: Cooperation in Biotechnology, Agriculture, Forestry, Fisheries and Food in the 7th FP”, Pushchino, Russia, 2-3 October. 2007: “Biocatalysis: the Italian contribution to industrial biotechnology”, "Joint Italian Japanese meeting on The challenge of biotechnologies”, Osaka, Giappone, 16 May. 2005: “Combining experimental and computational studies as a strategy towards a more rational biocatalysis”. BIOTRANS 2005, Delft, 3-8- July RESEARCH INTERESTS AND SKILLS Biobased chemistry, bioplastics, green chemistry, biomass valorization, biocomposite materials, biocatalysis, organic chemistry, computer-aided molecular simulation of enzymes; integration of molecular dynamics, molecular mechanics, docking, molecular descriptors based on GRID force field, for biocatalysis and rational enzyme engineering, machine learning, multiobjective optimization, chemometrics, 3D QSAR. HEAD OF SCIENTIFIC COMMITTEE OF INTERNATIONAL CONFERENCES “In silico enzyme design and screening”, Trieste, 7-9 May 2012. “Bioeconomy and Bio-based Industry for the Rural Renaissance of Regions (3BiR3)”. Trieste, 23-24 May 2019. MEMBER OF SCIENTIFIC COMMITTEE OF INTERNATIONAL CONFERENCES 2014: “Novel Enzymes”, Ghent, 14-17 October Since 2012: IFIB (Italian Forum on Industrial Biotechnology and Bioeconomy). Milan, 25-26 October, 2012; Napoli, 22-23 October 2013; Genova, 25-26 September 2014; Lodi 24-25 September 2015; Vicenza 22-23 September 2016; Roma 5-6 October 2017, Torino 4-5 October 2018. 2011: “BIOTRANS 2011”, Giardini Naxos, October 2-6 2010: “Novel enzymes”, Exeter, U.K., April 11-15. 2010: 14th International Biotechnology Symposium and Exhibition, Rimini, Italy, September 14-18. 2008: “Biocatalysis in non-conventional media”, Moscow, June 12-15.