Nobel Laureate in Chemistry Brian Kobilka took the audience on a fascinating journey into the invisible language of cells—the foundation of biological communication. At the heart of his groundbreaking research are G protein–coupled receptors, which regulate vital processes and represent one of the most revolutionary keys to contemporary biomedicine. This special evening at Trieste Next 2025 offered a unique opportunity to discover how these hidden molecular mechanisms shape life itself and open new horizons for the medicine of tomorrow