Human behavior, and in particular vaccine hesitancy, is a critical factor for the control of childhood infectious disease. Here we propose a spatio-temporal behavioral epidemiology model where the vaccine propensity depends on information that is non-local in space and in time. The properties of the proposed model are analyzed under different hypotheses on the spatio-temporal kernels tuning the vaccination response of individuals. As a main result, we could numerically show that vaccine hesitancy induces the onset of many dynamic patterns of relevance for epidemiology. In particular we observed: behavior-modulated patterns and spatio-temporal chaos. This is the first known example of human behavior-induced spatio-temporal chaos in statistical physics of vaccination. Patterns and spatio-temporal chaos are difficult to deal with, from the Public Health viewpoint, hence showing that vaccine hesitancy can cause them could be of interest. Additionally, we propose a new simple heuristic algorithm to estimate the Maximum Lyapunov Exponent.
