The REFREsh Danube project aims to reduce the landfilled amount of municipal solid waste, which is a source of water and soil pollution, by its use as refuse-derived fuel in the cement industry of Novi Sad (Serbia). The main actors involved are Lafarge Beočin Cement Factory, Municipality of Novi Sad, JPK Čistoća (waste-management company) and experts from interdisciplinary fields. The project addresses societal challenges on climate change, air, water and soil pollution as well as using the municipal solid waste as an alternative energy source in response to H2020 and Europe 2020 Strategy.