The aim of this paper is to outline the essential contribution of design practice in the teaching of Applied Ergonomics to Communication and to Architectural Design. In particular, students were asked to carry out a project using the theoretical teachings learned during the academic year. Only by “putting into practice” the knowledge acquired will the concepts be fully understood, which will also generate real “skills” to be included in the curriculum tools of students. From a practical point of view, two examples are presented. The first, developed with a group of students of my degree course in Communication Sciences at the University of Trieste, concerns the identification of etiquette rules for managers. The second relates to the planning of public housing according to ergonomic guidelines. The result was a work plan with highly innovative construction characteristics that improved usability for users and was compatible with different languages and cultures. This project was carried out with a group of my students from the Kazan State University of Architecture and Engineering, Republic of Tatarstan, Russian Federation and was successfully presented at the 16th International Architecture Biennale in Venice on 29 September 2018.