Abstract: The phenols and fatty acids profile and in vitro antioxidant and hypoglycaemic activity of
seed, peel, pulp or pulp plus seeds of Colombian fruits from Solanaceae and Passifloraceae families
were investigated. Ultra-High Performance Liquid Chromatography (UHPLC)-High Resolution Mass
Spectrometry (HRMS) revealed the presence of chlorogenic acid as dominant phenolic compound in
Solanaceae samples. Based on the Relative Antioxidant Score (RACI) and Global Antioxidant Score
(GAS) values, Solanum quitoense peel showed the highest antioxidant potential among Solanaceae
samples while Passiflora tripartita fruits exhibited the highest antioxidant effects among Passifloraceae
samples. P. ligularis seeds were the most active as hypoglycaemic agent with IC50 values of 22.6 and
24.8 g/mL against -amylase and -glucosidase, respectively. Considering that some of the most
promising results were obtained by the processing waste portion, its use as functional ingredients
should be considered for the development of nutraceutical products intended for patients with
disturbance of glucose metabolism.
