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Machine learning validation of the AVAS classification compared to ultrasound mapping in a multicentre study

Lawrie, Katerina
•
Waldauf, Petr
•
Balaz, Peter
altro
O'Neill, Stephen
2025
  • journal article

Periodico
SCIENTIFIC REPORTS
Abstract
The Arteriovenous Access Stage (AVAS) classification simplifies information about suitability of vessels for vascular access (VA). It's been previously validated in a clinical study. Here, AVAS performance was tested against multiple ultrasound mapping measurements using machine learning. A prospective multicentre international study (NCT04796558) with patient recruitment from March 2021-July 2024. Demographics, risk factors, vessels parameters, types of predicted and created VA (pVA, cVA) were collected. We modelled pVA and cVA using the Random Forest algorithm. Model performance was estimated and compared using Bayesian generalized linear models. ROC AUC with 95% credible intervals was the performance metric. 1151 patients were included. ROC AUC for pVA prediction by AVAS was 0.79 (0.77;0.82) and by mapping was 0.85 (0.83;0.88). ROC AUC for cVA prediction by AVAS was 0.71 (0.69;0.74) and by mapping was 0.8 (0.78;0.83). Using AVAS with other parameters increased the ROC AUC to 0.87 for pVA (0.84;0.89) and 0.82 (0.79;0.84) for cVA. Using mapping with other parameters increased the ROC AUC to 0.88 for pVA (0.86;0.91) and 0.85 (0.83;0.88) for cVA. Multiple mapping measurements showed higher performance at VA prediction than AVAS. However, AVAS is simpler and quicker, so may be preferable for routine clinical practice.
DOI
10.1038/s41598-025-86456-3
WOS
WOS:001401998100028
Archivio
https://hdl.handle.net/11368/3105019
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85216440001
https://www.nature.com/articles/s41598-025-86456-3
Diritti
open access
license:creative commons
license uri:http://creativecommons.org/licenses/by-nc-nd/4.0/
FVG url
https://arts.units.it/bitstream/11368/3105019/1/2025 - Scientific Reports 1.pdf
Soggetti
  • Arteriovenous acce

  • Classification system...

  • Dialysi

  • Mapping

  • Random forest

  • Renal replacement the...

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