We have correlated the onset age of refractory Epilepsy with efficacy of Lamotrigine used as add-on for a population of 389 patients treated for at least 2 years. Age groups were defined as ranging for 0 to 3 years, 4 to 12 years, 13 to 20 years and ultimately 21 years and beyond. The result obtained show similar responder frequency in the first two age groups for the Cryptogenetic and Symptomatic Generalized Epilepsy, and in the first three age groups for the Partial Epilepsy.
