Livelli sierici di BAFF e attecchimento della linfopoiesi B dopo il trapianto di cellule staminali allogeniche: Ruolo patogenetico nello sviluppo di graft-versus-host-disease cronica

We evaluated recovery and engraftment of B lymphocytes during the first 6 months after allogeneic stem cell transplantation (SCT) in 82 patients with or without chronic Graft versus Host Disease (cGvHD). The B cell compartment had stable engraftment of donor origin ad day 120 in all patients. BAFF serum levels had a peak at day 90, but this increase could not be correlated with the subsequent development of chronic GvHD