A computational investigation of the specific optical rotation and of the electronic circular dichroism spectra of
two chiral 1,4-dihydropyridazines was performed and compared with existing experimental data to verify a previous assignment of
their absolute configuration based on a well-accepted mechanism of catalysis of the organocatalyst used in their synthesis. Both
the optical rotation and circular dichroism calculations indicate that the absolute configuration is opposite to the one assigned on
the basis of the mechanism originally assumed. An alternative reaction mechanism is therefore suggested
