Supercritical fluids are particularly attractive as extracting agents because the solvent power can be manipulated over a wide range of temperatures and pressures. With increasing concern over the use of chemical solvents in the manufacture of pharmaceuticals, as well as the need for high-purity products, supercritical fluid technology are potential alternatives to the normal processing.
An alternative of minor psychological impact on the operators of the pharmaceutical industries is the use of a supercritical fluid in connection with the normal and traditional processing. The supercritical fluid can be used for the removal of the residual solvent left in the pharmaceutical form.
In this paper the results obtained in the removal of organic solvents both from polymers normally used in the pharmaceutical industry and from the final pharmaceutical forms are presented.
