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Reconstructing Phylogenetic Networks via Cherry Picking and Machine Learning

Giulia Bernardini
•
Leo van Iersel
•
Esther Julien
•
Leen Stougie
2022
  • conference object

Abstract
Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. In this paper, we apply the recently-introduced theoretical framework of cherry picking to design a class of heuristics that are guaranteed to produce a network containing each of the input trees, for practical-size datasets. The main contribution of this paper is the design and training of a machine learning model that captures essential information on the structure of the input trees and guides the algorithms towards better solutions. This is one of the first applications of machine learning to phylogenetic studies, and we show its promise with a proof-of-concept experimental study conducted on both simulated and real data consisting of binary trees with no missing taxa.
DOI
10.4230/lipics.wabi.2022.16
Archivio
https://hdl.handle.net/11368/3030019
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85137814035
https://drops.dagstuhl.de/opus/volltexte/2022/17050/
Diritti
open access
license:creative commons
license uri:http://creativecommons.org/licenses/by/4.0/
Soggetti
  • Phylogenetic

  • Hybridization

  • Cherry Picking, Machi...

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