The paper aims to be conceived as a kind of programmatic afterword for the present issue. It first describes the key concepts that orient the Real Smart Cities project, with a special focus on intelligence as a noetic process, and on the relation between territory, urban and non non-urban territorialisation and know ledge. Then, after an economic and socio socio-political analys analysis of the Anthropocene in the light of what the author defines as anthropy and neganthropy, the paper scribes the blueprint blueprints of a new interdisciplinary and international project based on the concepts enucleated above (de-proletarianisation, exosomatisation, noodiversity, among others).