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Approximating reproduction numbers: a general numerical method for age-structured models

Simone De Reggi
•
Francesca Scarabel
•
Rossana Vermiglio
2024
  • journal article

Periodico
MATHEMATICAL BIOSCIENCES AND ENGINEERING
Abstract
In this paper, we introduce a general numerical method to approximate the reproduction numbers of a large class of multi-group, age-structured, population models with a finite age span. To provide complete flexibility in the definition of the birth and transition processes, we propose an equivalent formulation for the age-integrated state within the extended space framework. Then, we discretize the birth and transition operators via pseudospectral collocation. We discuss applications to epidemic models with continuous and piecewise continuous rates, with different interpretations of the age variable (e.g., demographic age, infection age and disease age) and the transmission terms (e.g., horizontal and vertical transmission). The tests illustrate that the method can compute different reproduction numbers, including the basic and type reproduction numbers as special cases.
DOI
10.3934/mbe.2024236
Archivio
https://hdl.handle.net/11390/1272384
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85188342425
https://ricerca.unityfvg.it/handle/11390/1272384
Diritti
open access
Soggetti
  • basic reproduction nu...

  • structured population...

  • epidemic model

  • next generation opera...

  • pseudospectral colloc...

  • eigenvalue approximat...

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