“Why should a professor of mechanical engineering decide to study bone tissue? Well, simply because she is interested in preventing any kind of breakage, and fractures are not an exception!” I think enabling structures to resist the applied loads is an innate desire of all engineers. The complex and highly organized inner architecture of bones makes this challenge even more exciting. In such a complex material, loss of bone mass alone cannot justify all osteoporosis-related fractures. Being aware of this I decided to focus my research on the fracture risk assessment and the impact of the complex trabecular structure of bone on internal force distribution, the ultimate goal being to improve knowledge of each patient’s specific conditions.