Summary. Objective. To estimate the prevalence of Parkinson’s disease using electronic health archives and to obtain a knowledge base for its governance. Materials. Drug pre- scriptions, tax-exemptions and hospital discharge records relating to assisted of Health Services Agency “Triestina” in the year 2011. Results. We identi ed 909 cases (crude prev- alence rate: 380/100.000). The percentage contribution of drug prescriptions, tax-exemptions and hospital discharge records is: 81.5%, 36.1% and 35.2%. Conclusions. The use of drug prescriptions to detect patients with Parkinson’s disease can be e ectively supplemented by data of hospi- tal discharges and tax-exemptions, but they still show an underestimation of 17%.