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Synthesis and Characterization of Highly Water-Soluble Dendrofulleropyrrolidine Bisadducts with DNA Binding Activity

Montellano Lopez A.
•
Scarel F.
•
Rubio Carrero N.
altro
PRATO, MAURIZIO
2012
  • journal article

Periodico
ORGANIC LETTERS
Abstract
The synthesis, characterization and DNA binding studies of a series of polycationic fullerene adducts are reported. These cationic species, exhibiting reasonably high water solubility and a heterogeneous distribution of positive charges, can efficiently complex plasmid DNA. Electrophoresis studies show different DNA binding efficiencies for different adducts, some of which can be considered excellent candidates for DNA binding therapies.
DOI
10.1021/ol301946r
WOS
WOS:000308390000039
Archivio
http://hdl.handle.net/11368/2635510
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84866037379
Diritti
metadata only access
Soggetti
  • Fullerene

  • bisaddition

  • DNA delivery

Web of Science© citazioni
8
Data di acquisizione
Mar 27, 2024
Visualizzazioni
4
Data di acquisizione
Apr 19, 2024
Vedi dettagli
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