A detailed modelling of the ground motion in Trieste has been done for some scenario earthquakes, compatible with the seismotectonic regime of the region. Three-component synthetic seismograms (displacements, velocities and accelerations) have been analyzed to obtain significant parameters of engineering interest. The definition of the seismic input, derived from a comprehensive set of seismograms analyzed in the time and frequency domains, represents a powerful and convenient tool for seismic microzoning. Both modelling and observations show that site conditions in the centre of Trieste can amplify the ground motion at the bedrock by a factor of five, in the frequency range of engineering interest.