Two new glyceroglycolipids as well as three known ones were isolated from the glyceroglycolipids molecular species obtained from two less polar fractions of the MeOH extract of the plant Euphorbia nicaeensis All. using normal and reversed phase column flash chromatography. The structures of the isolated glyceroglycolipids were determined on the basis of chemical and spectroscopic evidences. Two new glyceroglycolipids were isolated for the first time from Euphorbiaceae, 2 was assigned as (2S)-2,3-O-di-(hexadecanoyl)-glyceryl-β-D-galactopyranoside and 5 as (2S)-3-O-(9, 12-octadecadienoyl)-glyceryl-β-D-galactopyranoside. The isolated glyceroglycolipids exhibited an interesting anti-inflammatory activity.
