In this work the solubility of natural and synthetic antioxidants in supercritical carbon dioxide is determined by dynamic method in the pressures range 130 to 250 bar at 308.1 and 333.1 K. The compounds considered are ascorbic acid, ascorbyl palmitate, gallic acid, propyl gallate, lauryl gallate, alpha tocopherol acid succinate and butyl hydroxyl anisole. The experimental data are correlated using the Peng-Robinson equation of state, the solutes properties are estimated by group contribution methods.