The ability of anthocyanins to permeate the gastric
mucosa can be suggested as a possible explanation of the fast
kinetics of plasma appearance of anthocyanins in rats and humans.
This paper presents an in vivo experiment aimed to prove
the involvement of the stomach in the absorption of grape anthocyanins
in rats. The required analytical selectivity and sensitivity
was achieved by high-performance liquid chromatography,
diode array detection and mass spectrometry. Malvidin 3-glucoside
appeared in both portal and systemic plasma after only
6min. The average concentrations measured in portal and systemic
plasma were 0.650 +/- 0.162 µM and 0.234 #0.083 µM
(mean +/- S.E.M.), respectively.
