For relevant engineering purposes, or for historical buildings and monuments, a viable alternative to standard estimates of seismic hazard is rep- resented by the use of the scenario earthquakes, characterized in terms of mag- nitude, distance and faulting style, and taking into account the complexity of the kinematic source rupturing process. This multi-scenario-based Neo-Determi- nistic Seismic Hazard Assessment (NDSHA) method naturally supplies realistic time series of ground motions that are readily applicable to engineering anal- yses. Such a methodology has been successfully applied to many urban areas worldwide for the purpose of seismic microzoning, to strategic buildings, life- lines and cultural heritage sites, and in this paper its application is presented for the city of Trieste.