cervical lymphadenopathy is usually related to the presence of an inflammatory disease or to a malignant localization. In the event of metastatic findings, the thyroid gland is the most likely primary site of a tumor. Metastatic lymphadenopathy represents a challenge when the primary tumor is unknown. A 64-year-old female with a supraclavicular palpabel mass in the absence of underlying thyroid disease underwent ultrasonography of the neck, biopsy of the pathological lymph node, fluorodesoxyglucose-positron emission tomography (FDG-PET) and colonoscopy until right colon cancer was diagnosed. FDG-PET is a fast and reliable tool to discover the primary site of cervical masses of unknown origin
