Anti-Mu ̈llerian hormone (AMH) has become the ‘molecule of the moment’ in the field of reproductive endocrinology.
Indeed, it is valuable as a means of increasing understanding of ovarian pathophysiology and for guiding clinical management across
a broad range of conditions. However, no normative values have been established for circulating AMH in healthy women. In this
cross-sectional study, 277 healthy females (aged 18–50 years) were included. AMH was measured by commercial enzyme-linked
immunosorbent assay. Serum AMH concentrations show a progressive decline with female ageing. The age-related changes in
AMH were best fitted by a polynomial function. Mean AMH concentrations were not modified by past use of oral contraceptive
and were independent of parity of women. Age-specific normative values for circulating AMH concentration were established.
AMH concentrations seem to be independent of the reproductive history of the patient
