Fullerene derivatives have interesting biological activities that make them good candidates for applications in medicinal
chemistry. However, the development of these applications is hampered by the fact that fullerene derivatives are insoluble in
water and polar media. We present here a general method for the preparation of N-functionalized fulleropyrrolidines with
solubilizing groups via 1,3-dipolar cycloaddition of azomethine ylides to C .
