Aim: To provide an updated, evidence-based guidance on preventive strategies for MIH management. Methods: The search process was conducted on PubMed®/MEDLINE and included the most recent (last l0 years), highest-quality English-language dental literature focused on preventive strategies in MIH patients (<18 years). Results: Preventive measures - including fluoride-, casein-, calcium glycerophosphate-, arginine-based products; bioactive glasses; biomimetic hydroxyapatite; self-assembling peptides; ozone and laser therapies; silver diamine fluoride; resin infiltration; and fissure sealants are presented. Conclusion: Early diagnosis is essential for the implementation of preventive strategies. Given the absence of a standardised treatment protocol for MIH, therapeutic interventions should be carefully customised based on the severity of the condition, the patient's age, level of cooperation, and specific clinical needs. Adopting a combined preventive approach may significantly improve long-term outcomes.
