Acoustics represent one of the most important comfort parameters for autistic people, their relatives and caregivers. Many design criteria of residential spaces related to autistic user describes the peculiarities of acoustic theme as their primary target. But an approach based specific acoustic parameters of international standards is still missing. For the SENSHome project, we had to figure out what the ideal interior acoustic conditions were for a space – a house – that could be autistic-friendly and, at the same time, accommodate smart support systems. The reverberation of a living space can be controlled by the insertion of sound absorbing elements of various types, but in the case of autistic users, literature suggests that it is necessary to follow the fundamental concept of “user centered design approach”.