This paper deals with the women’s participation at the D’Annunzio’s impresa di Fiume (En-deavor of Fiume, 1919-1920): Margherita Besozzi and Margherita Incisa di Camerana, as well as lesser-known characters such as Nicolina Fabris, the mother of the grenadiers and Maria Vitali, the custodian of the dead. Finally, mention is made of the social commitment of the educationalist Gemma Harasim, from Fiume who was ahead of her times and who left a lasting imprint on educational modernity and on female emancipation.