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Non-invasive cerebellar stimulation in neurodegenerative ataxia: A literature review

Benussi A.
•
Pascual-Leone A.
•
Borroni B.
2020
  • journal article

Periodico
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Abstract
Cerebellar ataxias are a heterogenous group of degenerative disorders for which we currently lack effective and disease-modifying interventions. The field of non-invasive brain stimulation has made much progress in the development of specific stimulation protocols to modulate cerebellar excitability and try to restore the physiological activity of the cerebellum in patients with ataxia. In light of limited evidence-based pharmacologic and non-pharmacologic treatment options for patients with ataxia, several different non-invasive brain stimulation protocols have emerged, particularly employing repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) techniques. In this review, we summarize the most relevant rTMS and tDCS therapeutic trials and discuss their implications in the care of patients with degenerative ataxias.
DOI
10.3390/ijms21061948
WOS
WOS:000529890200044
Archivio
https://hdl.handle.net/11368/3096886
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85081614500
https://www.mdpi.com/1422-0067/21/6/1948
https://pmc.ncbi.nlm.nih.gov/articles/PMC7139863/
Diritti
open access
license:creative commons
license uri:http://creativecommons.org/licenses/by/4.0/
FVG url
https://arts.units.it/bitstream/11368/3096886/1/ijms 2020.pdf
Soggetti
  • Cerebellar ataxia

  • Neurodegenerative ata...

  • Non-invasive brain st...

  • Therapy

  • Transcranial direct c...

  • Transcranial magnetic...

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