The surgical treatment of non-metastatic melanoma in a Clinical National Melanoma Registry Study Group (CNMR): a retrospective cohort quality improvement study to reduce the morbidity rates

Vecchiato A.; Mocellin S.; Del Fiore P.; Tosti G.; Ascierto P. A.; Corradin M. T.; De Giorgi V.; Giudice G.; Queirolo P.; Ferreli C.; Occelli M.; Giordano M.; Trevisan G.; Mascheroni L.; Testori A.; Spina R.; Buja A.; Cavallin F.; Caraco C.; Sommariva A.; Rossi C. R.; Asero S.; Barbati R.; Bianchi L.; Bruder F.; Catricala C.; Cinieri S.; Del Vecchio M.; Di Filippo F.; Fargnoli M. C.; Fierro M. T.; Forcignano R.; Guidoboni M.; Iacono C.; Lospalluti L.; Maio M.; Milesi L.; Moise G.; Moretti G.; Pellicano R.; Pizzichetta M. A.; Rinaldi G.; Sanna G.; Staibano S.; Visini M.; Zannetti G.; Zichichi L.

The surgical treatment of non-metastatic melanoma in a Clinical National Melanoma Registry Study Group (CNMR): a retrospective cohort quality improvement study to reduce the morbidity rates

Vecchiato A.

•

Mocellin S.

•

Del Fiore P.

altro

Zichichi L.

2021

journal article

Periodico

BMC CANCER

Abstract

Background: Reproducible, high-quality surgery is a key point in the management of cancer patients. Quality indicators for surgical treatment of melanoma has been presented with benchmarks but data on morbidity are still limited. This study presents the quality indicators on morbidity after surgical treatment for non-metastatic skin melanoma in an Italian registry. Methods: Data were extracted from the Central National Melanoma Registry (CNMR) promoted by the Italian Melanoma Intergroup (IMI). All surgical procedures (WE, SNLB or LFND) for non-metastatic skin melanoma between January 2011 and February 2017 were evaluated for inclusion in the study. Only centers with adequate completeness of information (> 80%) were included in the study. Short-term complications (wound infection, dehiscence, skin graft failure and seroma) were investigated. Results: Wound infection rate was 1.1% (0.4 to 2.7%) in WE, 1.3% (0.7 to 2.5%) in SLNB and 4.1% (2.1 to 8.0%) in LFND. Wound dehiscence rate was 2.0% (0.8 to 5.1%) in WE, 0.9% (0.2 to 3.0%) in SLNB and 2.8% (0.9 to 8.6%) in LFND. Seroma rate was 4.2% (1.5 to 11.1%) in SLNB and 15.1% (4.6 to 39.9%) in LFND. Unreliable information was found on skin graft failure. Conclusions: Our findings contribute to available literature in setting up the recommended standards for melanoma centers, thus improving the quality of surgery offered to patients. A consensus on the core issues around surgical morbidity is needed to provide practical guidance on morbidity prevention and management.