"Macroecology describes large-scale patterns, but microecology is fundamental to understand processes. In view of the..." Evaluation of: [Paine RT. Macroecology: does it ignore or can it encourage further ecological syntheses based on spatially local experimental manipulations? (American Society of Naturalists address). Am Nat. 2010 Oct; 176(4):385-93; doi: 10.1086/656273]. Faculty of 1000, 24 Sep 2010. F1000.com/5203956