With the advent of ultrasound-guided, multiple diagnostic and staging prostates biopsies in conjunction with careful pathological evaluation, a conservative strategy can be considered for treatment of premalignant lesions and prostatic cancer. A nerve sparing tecnique can be attempted into a patient with prostatic cancer, even with cryoablation procedures. Only a long term follow-up study of these and other patients will allow us to determine the real efficacy of this tecnique, but it must be remembered that, in case of recurrence, cryoablation can be repeated