The production cross sections of D0 and Λ+c hadrons originating from beauty-hadron decays (i.e., non prompt) were measured for the first time at midrapidity (jyj < 0.5) by the ALICE Collaboration in proton-proton collisions at a center-of-mass energy √s = 13 TeV. They are described within uncertainties by perturbative QCD calculations employing the fragmentation fractions of beauty quarks to baryons measured at forward rapidity by the LHCb Collaboration. The b ̄
b production cross section per unit of rapidity at midrapidity, estimated from these measurements, is dσb ̄b/d/dy|y|<0.5 = 83.1 +/- 3.5 (stat) +/- 5.4 (syst)+12.3 −3.2 (extrap) μb. The baryon-to-meson ratios are computed to investigate the hadronization mechanism of beauty quarks. The nonprompt Λ+c =D0 production ratio has a similar trend to the one
measured for the promptly produced charmed particles and to the p=π+ and Λ=K0S ratios, suggesting a
similar baryon-formation mechanism among light, strange, charm, and beauty hadrons. The pT -integrated
nonprompt Λ+c =D0 ratio is found to be significantly higher than the one measured in eþe− collisions.