A new water-soluble multi-charged monoadduct fullero[
60]pyrrolidine derivative with three ethylene glycol chains
and three ammonium groups has been synthesized by means
of two alternative synthetic pathways. Increasing the concentration
of this C60 derivative did not show a significant modification
of concentration of superoxide anion radical O2
·−,generated by the xanthine/xanthine oxidase system. Moreover,
this C60 derivative was ineffective for neuroprotection
in quantitative assessment of a neuronal injury considered to
occur via radicals
