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Five-Year Longitudinal Assessment of Self-reported COVID-19-Related Chemosensory Dysfunction

Boscolo-Rizzo, Paolo
•
Spinato, Giacomo
•
De Colle, Rebecca
altro
Tirelli, Giancarlo
2026
  • journal article

Periodico
CLINICAL INFECTIOUS DISEASES
Abstract
This study presents a five-year follow-up of 436 patients who experienced mild COVID-19 in early 2020, focusing on long-term smell and taste dysfunction. At the onset, 66.7% reported altered chemosensory perception. Although most recovered over time, 7.6% still reported dysfunction after five years. Recovery rates steadily improved, reaching 91.1% among those initially affected. Despite the improvements, persistent symptoms remain a concern for a subset of patients, highlighting ongoing quality-of-life and safety issues. The study underscores the need for long-term monitoring and potential rehabilitation strategies for chemosensory dysfunction. Limitations include self-reported data, no objective testing, and focus on pre-Omicron infections.
DOI
10.1093/cid/ciaf331
WOS
WOS:001533987400001
Archivio
https://hdl.handle.net/11368/3113479
https://academic.oup.com/cid/article/81/6/e729/8210703
https://ricerca.unityfvg.it/handle/11368/3113479
Diritti
closed access
license:copyright editore
license uri:iris.pri02
FVG url
https://arts.units.it/request-item?handle=11368/3113479
Soggetti
  • Chemosensory dysfunct...

  • COVID-19

  • Long-term follow-up

  • Olfactory impairment

  • Taste disorder

  • Recovery

  • Smell loss

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