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In vitro models for the study of non-alcoholic fatty liver disease.

N. C. Chavez Tapia
•
N. Rosso
•
TIRIBELLI, CLAUDIO
2011
  • journal article

Periodico
CURRENT MEDICINAL CHEMISTRY
Abstract
Non-alcoholic fatty liver disease is regarded as the hepatic manifestation of metabolic syndrome and is an important and common cause of chronic liver disease with a potential to develop end-stage liver disease. While important advances in the pathophysiology have been achieved using genetically modified and diet-induced animal models, in-vitro models have been only recently proposed. These models include primary culture and immortalized cell lines. Here we critically review the characteristics of the in vitro models described, the advantages and limitations of the in vitro approach, and the results derived.
WOS
WOS:000288989500009
Archivio
http://hdl.handle.net/11368/2491346
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-79952776936
Diritti
metadata only access
Soggetti
  • Animals, Cell Line, D...

  • adverse effects, Fatt...

  • chemically induced/me...

Scopus© citazioni
38
Data di acquisizione
Jun 7, 2022
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Visualizzazioni
4
Data di acquisizione
Apr 19, 2024
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