Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)
SEGAT, LUDOVICA
•
Guimarães, Rafael L
•
Brandão, Lucas A. C
altro
CROVELLA, SERGIO
2010
Periodico
INTERNATIONAL JOURNAL OF DERMATOLOGY
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.
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