A fullerene derivative containing a free amino group has been condensed with N-Fmoc-L-glutamic acid r-tert-butyl ester to give a C60-functionalized
amino acid. The carboxylic end of this amino acid has been deprotected in acidic conditions, and the resulting acid has been used for
solid-phase peptide synthesis. The final peptide, cleaved from the resin, was very soluble in water solutions and showed antimicrobial activity
against two representative bacteria
