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OCT-based deep-learning models for the identification of retinal key signs

Leandro, Inferrera
•
Lorenzo, Borsatti
•
Aleksandar, Miladinovic
altro
Daniele, Tognetto
2023
  • journal article

Periodico
SCIENTIFIC REPORTS
Abstract
A new system based on binary Deep Learning (DL) convolutional neural networks has been developed to recognize specific retinal abnormality signs on Optical Coherence Tomography (OCT) images useful for clinical practice. Images from the local hospital database were retrospectively selected from 2017 to 2022. Images were labeled by two retinal specialists and included central fovea cross-section OCTs. Nine models were developed using the Visual Geometry Group 16 architecture to distinguish healthy versus abnormal retinas and to identify eight different retinal abnormality signs. A total of 21,500 OCT images were screened, and 10,770 central fovea cross-section OCTs were included in the study. The system achieved high accuracy in identifying healthy retinas and specific pathological signs, ranging from 93 to 99%. Accurately detecting abnormal retinal signs from OCT images is crucial for patient care. This study aimed to identify specific signs related to retinal pathologies, aiding ophthalmologists in diagnosis. The high-accuracy system identified healthy retinas and pathological signs, making it a useful diagnostic aid. Labelled OCT images remain a challenge, but our approach reduces dataset creation time and shows DL models' potential to improve ocular pathology diagnosis and clinical decision-making.
DOI
10.1038/s41598-023-41362-4
WOS
WOS:001062861100015
Archivio
https://hdl.handle.net/11368/3057599
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85169693005
https://www.nature.com/articles/s41598-023-41362-4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480174/
Diritti
open access
license:creative commons
license uri:http://creativecommons.org/licenses/by/4.0/
FVG url
https://arts.units.it/bitstream/11368/3057599/1/OCT-based deep-learning models for the identification of retinal key signs Sc Rep 2023.pdf
Soggetti
  • Deep Learning

  • Fovea Centrali

  • Human

  • Retina

  • Retrospective Studie

  • Tomography, Optical C...

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