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Bioink: a 3D-bioprinting tool for anticancer drug discovery and cancer management

Tiwari A. P.
•
Thorat N. D.
•
Pricl S.
altro
Townley H.
2021
  • journal article

Periodico
DRUG DISCOVERY TODAY
Abstract
‘Bioinks’ are important tools for the fabrication of artificial living-tissue constructs that are able to mimic all properties of native tissues via 3D bioprinting technologies. Bioinks are most commonly made by incorporating live cells of interest within a natural or synthetic biocompatible polymeric matrix. In oncology research, the ability to recreate a tumor microenvironment (TME) using by 3D bioprinting constitutes a promising approach for drug development, screening, and in vitro cancer modeling. Here, we review the different types of bioink used for 3D bioprinting, with a focus on its application in cancer management. In addition, we consider the fabrication of bioink using customized materials/cells and their properties in the field of cancer drug discovery.
DOI
10.1016/j.drudis.2021.03.010
WOS
WOS:000684572800005
Archivio
http://hdl.handle.net/11368/2997251
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85103536793
https://www.sciencedirect.com/science/article/pii/S1359644621001446
Diritti
open access
license:copyright editore
license:creative commons
license uri:http://creativecommons.org/licenses/by-nc-nd/4.0/
FVG url
https://arts.units.it/request-item?handle=11368/2997251
Soggetti
  • Bioink

  • 3D-bioprinting

  • anticancer drug disco...

  • cancer management

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