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Optimal control of a SIR epidemic with ICU constraints and target objectives

Avram F.
•
Freddi L.
•
Goreac D.
2022
  • journal article

Periodico
APPLIED MATHEMATICS AND COMPUTATION
Abstract
The aim of this paper is to provide a rigorous mathematical analysis of an optimal control problem with SIR dynamics main feature of our study is the presence of state constraints (related to intensive care units ICU capacity) and strict target objectives (related to the immunity threshold). The first class of results provides a comprehensive description of different zones of interest using viability tools. The second achievement is a thorough mathematical analysis of Pontryagin extremals for the aforementioned problem allowing to obtain an explicit closed-loop feedback optimal control. All our theoretical results are numerically illustrated for a further understanding of the geometrical features and scenarios.
DOI
10.1016/j.amc.2021.126816
WOS
WOS:000723085200006
Archivio
http://hdl.handle.net/11390/1217915
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85119987361
https://ricerca.unityfvg.it/handle/11390/1217915
Diritti
closed access
Soggetti
  • Epidemic

  • Feedback control

  • Optimal control

  • Pontryagin principle

  • SIR

  • State constraint

  • Viability

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