Oxygen-17 NMR Studies of N-Nitrosamines

Natural abundance O-17 NMR data for seven aliphatic, nine cyclic and thirteen aromatic N-nitrosamines, recorded at room temperature in acetonitrile, are reported. Differences in chemical shifts among and within the three groups are discussed in terms of electronic and steric effects. The sigma(+) value for the N-nitrosamine group was estimated. A comparison between amides and N-nitrosamines was made.