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New multidrug (dexamethasone and theophylline) PEG-conjugate: Synthesis, in vitro release studies and intestinal permeability

ZACCHIGNA, MARINA
•
CATENI, FRANCESCA
•
VOINOVICH, DARIO
altro
BONORA, GIAN MARIA
2009
  • journal article

Periodico
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Abstract
A branched high-molecular weight multimeric PEG (MultiPEG), synthesized with a simple assembling procedure that devised the introduction of functional groups with divergent and selective reactivity, was employed as a drug carrier. The permeation process across the intestinal membrane of the same macromolecular conjugate was investigated, mathematically discussed and interpreted according to “Fick’s law”.
Archivio
http://hdl.handle.net/11368/2262138
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-68549109433
Diritti
metadata only access
Soggetti
  • Macromolecular prodru...

  • MultiPEG

  • Intestinal permeabili...

  • Dexamethasone

  • Theophylline

Visualizzazioni
1
Data di acquisizione
Apr 19, 2024
Vedi dettagli
google-scholar
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