This paper reports the results of a structural study of the deformational belt developing around the Giudicarie tectonic lineament in the central Southern Alps of Italy. Three different, non-coaxial systems of deformation has been recognized from the analysis of the mesoscopic structures such as systems of veins and pressure-solution clevages, fold system and fold superposition, and the stress inversion from fault populations. The structural setting of the Giudicarie belt results from the superposition in time of these deformational systems, which correspond to diverse tectonic stages of the neoalpine tectonics.