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Analysis of the spatial and dynamical properties of a multiscale model of intestinal crypts

CARAVAGNA, GIULIO
•
GRAUDENZI, ALEX
•
ANTONIOTTI, MARCO
•
De Matteis, G.
2013
  • conference object

Periodico
ELECTRONIC PROCEEDINGS IN THEORETICAL COMPUTER SCIENCE
Abstract
The preliminary analyses on a multiscale model of intestinal crypt dynamics are here presented. The model combines a morphological model, based on the Cellular Potts Model (CPM), and a gene regulatory network model, based on Noisy Random Boolean Networks (NRBNs). Simulations suggest that the stochastic differentiation process is itself sufficient to ensure the general homeostasis in the asymptotic states, as proven by several measures.
DOI
10.4204/EPTCS.130.12
Archivio
http://hdl.handle.net/11368/2956248
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85066844385
Diritti
metadata only access
Soggetti
  • Simulation

  • Cellular Potts Model

  • Noisy Random Boolean ...

  • Multicellular Modelin...

Scopus© citazioni
0
Data di acquisizione
Jun 7, 2022
Vedi dettagli
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