SUPPLEMENT TO INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS
Abstract
Objectives: To analyze risk of pre-term delivery in nulliparous
women over 40 years of age.
Materials: We retrospectively analyzed neonatal and pregnancy
outcomes of 10488 nulliparous women, who delivered between
2001 and 2010 in two third level Clinics of North-East Italy, 496 of
which have delivered after 40 years of age.
Methods: Data was analyzed by R (version 2.13.1), considering
significant p < 0.05.
Results: In multivariate logistic regression model were independent
risk factors for preterm delivery before 37 gestational weeks:
delivery after 40 years of age, pregnancy related hypertensive
disorders, SGA (<10th centile), maternal diabetes, and twin
pregnancies. Moreover, in multivariate logistic regression model
were independent risk factors for preterm delivery before 34
gestational weeks: pregnancy related hypertensive disorders, and
twin pregnancies.
Conclusions: Even if advanced maternal age is a risk factor
for preterm delivery before 37th gestational week it is not
an independent risk factor for pre-term delivery before 34th
gestational week.
