The research aims to contribute to the definition of new planning paradigms aimed at fostering ecological transition and achieving climate neutrality. It focuses on the relationship between territorial resilience and water management, which—shifting from a risk factor to a design framework—serves to redefine the interconnections among settlements, infrastructures, and landscapes. Through this perspective, the study promotes a circular, self-sufficient, and resilient territorial model. The investigation is applied to the territories of the Lower Plain of Friuli Venezia Giulia, with the objective of attaining climate neutrality at both urban and regional scales.