In the context of ground states of quantum many-body systems, the locality of entanglement between connected regions of space is directly tied to the locality of the corresponding entanglement Hamiltonian: the latter is dominated by local, few-body terms. In this work, we introduce the negativity Hamiltonian as the (non-Hermitian) effective Hamiltonian operator describing the logarithm of the partial transpose of a many-body system. This allows us to address the connection between entanglement and operator locality beyond the paradigm of bipartite pure systems. As a first step in this direction, we study the structure of the negativity Hamiltonian for fermionic conformal field theories and a free-fermion chain: in both cases, we show that the negativity Hamiltonian assumes a quasilocal functional form, that is captured by simple functional relations.
